π©Ί USMLE Step 1 High-Yield Video Review
Comprehensive topic-based video preparation aligned with First Aid for the USMLE Step 1 Exam
20
Expert Videos
11
Organ Systems
100%
First Aid Aligned
Biochemistry & Molecular Biology
Metabolism pathways, glycolysis, gluconeogenesis, and glycogen regulation
Human Metabolism Map I β Glycolysis
Armando Hasudungan covers each step of glycolysis with hand-drawn illustrations, highlighting key enzymes (e.g. hexokinase, PFK-1, pyruvate kinase) and regulatory points for efficient glucose breakdown.
Human Metabolism Map II β Gluconeogenesis & Glycogenesis
Armando explains how the body generates and stores glucose. He walks through gluconeogenesis (reverse of glycolysis) and glycogen synthesis/breakdown pathways with clear visuals, linking them to First Aid’s biochemistry sections.
Pharmacology
Chemotherapy agents and autonomic nervous system pharmacology
Pharmacology β Chemotherapy agents
Armando Hasudungan visually summarizes major chemotherapy drug classes. He illustrates mechanisms of action for alkylating agents, antimetabolites, topoisomerase inhibitors, antimitotics, and others, connecting each class to key diseases and toxicities often tested on Step 1.
Pharmacology β Autonomic Nervous System (MADE EASY)
Speed Pharmacology provides a rapid, high-yield review of autonomic drug mechanisms. This video covers sympathetic and parasympathetic receptors (Ξ±/Ξ² receptors, muscarinic/nicotinic), and key drugs acting on them, with mnemonic tips and analogies to make complex pharmacology concepts clear.
Cardiovascular System
Cardiac electrophysiology, muscle contraction, and hypertension
Heart Physiology I (Cardiac Myocyte and Membrane Potential)
Armando Hasudungan explains cardiac electrophysiology. In this animation, he details the cardiac myocyte action potential and ion channel behavior (NaβΊ, CaΒ²βΊ, KβΊ channels) that govern heart rhythm. The video links these mechanisms to concepts in cardiac physiology in First Aid.
Heart Physiology II (Muscle contraction and Pacemaker activity)
Armando continues with cardiac physiology. He shows how the electrical activity triggers muscle contraction and how pacemaker cells (SA/AV nodes) generate rhythmic impulses. Key concepts (e.g. calcium-induced calcium release, funny current) are tied to First Aid cardiac physiology.
Hypertension Explained Clearly β Causes, Diagnosis, Medications
Dr. Roger Seheult (MedCram) reviews hypertension pathophysiology in a clear lecture format. He covers the regulation of blood pressure (renal, vascular, neural factors), diagnostic thresholds, and outlines major antihypertensive drug classes. This board-style review links directly to First Aid’s cardiovascular pharmacology and path sections.
Respiratory System
Lung development, physiology, and respiratory pathology
High Yield Pulmonology Review Pt 1 (Lung Development and Physiology)
Conan Liu follows the First Aid outline for pulmonary content. Part 1 covers lung embryology/development and basic respiratory physiology (ventilation, lung volumes, diffusion). The presenter emphasizes high-yield facts (e.g. alveolar gas exchange, oxygen-hemoglobin curve) relevant for Step 1.
High Yield Pulmonology Review Pt 2 (Respiratory Pathology)
Conan Liu’s Part 2 continues with pulmonary pathology. Key diseases (e.g. obstructive vs. restrictive lung diseases, acute respiratory distress syndrome) and their pathophysiology are explained in First Aid order. High-yield boards-style review is combined with concise pathology summaries.
Renal System
Kidney function and acid-base balance
Role of the Kidney in Acid-Base Balance (Renal Physiology)
Osmosis provides an animated review of renal contribution to acid-base homeostasis. The video explains bicarbonate reabsorption, HβΊ secretion, and renal compensation for acidosis/alkalosis. This concise lecture aligns with First Aid’s renal physiology and acid-base content.
Gastrointestinal System
GI pathology including IBD, PUD, and malabsorption
High Yield Gastrointestinal Pathology β GI Part 1
Conan Liu’s rapid review of GI pathology follows First Aid’s gastrointestinal section. In Part 1, he covers high-yield topics such as esophageal disorders, gastritis/peptic ulcer disease, malabsorption syndromes, and inflammatory bowel disease. The video emphasizes mnemonic tricks and first aid correlations for these GI pathologies.
Endocrine System
Insulin, glucagon, and blood glucose regulation
Insulin and Glucagon Overview (Endocrine Physiology)
Osmosis breaks down the regulation of blood glucose by insulin and glucagon. This video explains where each hormone is produced, how they interact to raise or lower blood sugar, and their downstream effects on metabolism. Key First Aid concepts (diabetes pathology and metabolic regulation) are highlighted.
Microbiology & Immunology
Adaptive immunity, viral/bacterial structure, and vaccinations
Immunology β Adaptive Immune System
Armando Hasudungan’s immunology video illustrates the adaptive immune response. It covers antigen presentation, T-cell and B-cell activation, affinity maturation, and class-switching. The visual format ties these mechanisms to immunology topics in First Aid, helping beginners grasp how adaptive immunity works.
Viral Structure and Functions (Virology)
Osmosis provides an overview of viruses, explaining the structures of DNA and RNA viruses. The video covers common virus families, their capsid/envelope characteristics, and replication strategies. High-yield points (e.g. mode of transmission, iconic diseases) are linked to First Aid microbiology sections.
Bacterial Structure and Functions
In this Osmosis video, basic bacterial anatomy and physiology are explained. Key topics include gram-positive vs gram-negative cell walls, common cellular structures (flagella, pili), and growth requirements. The concise review sets up understanding for antibiotics and pathogenesis as covered in First Aid microbiology.
Vaccinations for the USMLE Step 1
This Physeo video (Malke Asaad, M.D.) reviews high-yield vaccine concepts for Step 1. It explains the different vaccine types (live-attenuated, inactivated, conjugate, etc.), important immunization schedules, and representative diseases/vaccines. The concise format hits key First Aid immunology points about immunizations and herd immunity.
Behavioral Science & Biostatistics
Biostatistics fundamentals and behavioral science ethics
Biostatistics SUMMARY Step 1 β The Basics
Dr. Randy Neil provides a concise video covering foundational biostatistics and epidemiology. He reviews study types, sensitivity/specificity, predictive values, and basic statistical concepts in a digestible format. This summary hits the core biostat topics listed in First Aid for rapid Step 1 review.
Behavioral Science and Ethics USMLE Step 1/2 CK β 25 High-Yield Topics!
Malke Asaad, M.D. (USMLE Rapid Review) goes through 25 key topics in behavioral science and ethics. This video aligns with First Aid’s behavioral chapters, covering concepts like ethical principles, patient interactions, psychiatric disorder overviews, and test-taking strategies for biostat/behavioral questions.
Musculoskeletal System
MSK anatomy and high-yield pathology
USMLE STEP 1 HIGH YIELD MSK & ANATOMY
A concise review of musculoskeletal high-yield topics. This video (by Med Student Success) covers important anatomical landmarks and musculoskeletal pathology (e.g. bone tumors, muscle metabolism) in a First Aid-driven format. Key facts are emphasized through fast-paced narration and visuals.
Reproductive System
Embryology, hormonal regulation, and reproductive pathology
USMLE STEP 1 HIGH YIELD REPRO
This video reviews high-yield reproductive system topics for Step 1. It covers embryologic development of the reproductive tract, common pathologies (e.g. disorders of sexual development, hormonal regulation), and integrates First Aid reproductive physiology and pathology points.
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